Febrile neutropenia: Median door-to-needle time – Results of an initial audit

An Audit of Perioperative Antimicrobial Prophylaxis: Time to Take Action

Capillary refill time in febrile neutropenia.

INTRODUCTION Febrile neutropenia is a major cause of morbidity and mortality in patients presenting this condition following chemotherapy against several malignancies. OBJECTIVE To evaluate if capillary refill time (CRT) allows the prediction of poor clinical outcome with or without antibiotic dose escalation. METHOD Capillary refill time was assessed in 50 patients with febrile neutropenia...

Prospective study of "door to needle time" in meningococcal disease.

OBJECTIVE To measure the promptness of antibiotic treatment in children with meningococcal disease. METHODS "Door to needle time" for parenteral antibiotics in children with meningococcal disease was recorded prospectively as part of a larger study. The time from arrival at hospital until the first dose of parenteral antibiotics was recorded in 100 children with meningococcal disease (median ...

Factors Associated with Adverse Outcome in Pediatric Febrile Neutropenia: Results from a Tertiary Care Hospital

Background Febrile neutropenia with childhood cancer alters the outcome significantly. To study the clinical and laboratory parameters, which predict the outcome among cancer patients with febrile neutropenia this study was undertaken. Materials and Methods The study included children less than 18 years with febrile neutropenia episodes. Clinical and hematological / laboratory parameters were r...

Management of Febrile Neutropenia

Bacterial Pathogens Bacteria are the predominant organisms. In the late 1950’s/early 1960’s Gram+ve organisms were the commonest, particularly Staphylococcus aureus. The late 1960’s/early 1970’s were typified by Gram-ve of gastrointestinal tract origin, particularly Escherischia coli, Klebsiella spp and Pseudomonas spp. By the 1990’s Staphylococcus spp including coagulase negative organisms, St...